Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells
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چکیده
منابع مشابه
Gastric mucus secretion in ranitidine-treated patients.
treatment the facial paraesthesia had ceased. After a further two days sensation was normal in the right arm and the sensory level on the trunk had descended to T6 on the right and T8 on the left. Grip in the right hand had improved (grade 3-4) and he was again able to move his right leg at the hip and knee (grade 3) and ankle (grade 2). After 10 days' treatment he was able to walk with a singl...
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Macrolide antibiotics such as erythromycin (EM) and azithromycin (AZM) are beneficial in the treatment of mucus hypersecretion in inflammatory pulmonary diseases. Several indirect and direct mechanisms of action have been proposed. This study investigates the direct effect of macrolides on secretory function of isolated submucosal mucous gland cells (SMGCs). We hypothesize that macrolides inhib...
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It is well established that the esophageal distention (ED) leads to gastric relaxation, partly by vago-vagal reflex, but till now, the effect of ED on gastric acid secretion has not been investigated. The aim of this study was to investigate the effect of ED on basal and stimulated gastric acid secretion. Methods: Adult male Wistar rats (200-240 g) were deprived of food but not the water 24 h b...
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Introduction: The protective and antisecretory effects of dopamine agonists on the stomach have been already reported, but the effect of bromocriptine (D2 dopamine agonist) on histamine stimulated gastric acid secretion (GAS) needs to be investigated. Methods: For gastric sampling, animals were anesthetized and a polyethylen tube was introduced into the stomach through esophagus. A cannula ...
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ژورنال
عنوان ژورنال: Genes to Cells
سال: 2006
ISSN: 1356-9597,1365-2443
DOI: 10.1111/j.1365-2443.2006.00964.x